Scientist I - MSAT (Cell & Gene Therapy) (Contractor)

Remote Full-time
About the position Legend Biotech is seeking Scientist I - MSAT (Cell & Gene Therapy) as part of the Manufacturing Technology team based in Somerset, NJ. We are seeking a motivated Scientist I to join our MSAT team, supporting the development, troubleshooting, and optimization of automated manufacturing processes for CAR-T and other cell therapy products. Under the guidance of senior staff, this role will perform bio-pilot run experiments, technology evaluations, and process improvement studies. The position will directly contribute to manufacturing robustness and efficiency by executing laboratory work, assisting in equipment testing, and analyzing process data. Responsibilities • Execute bench-scale experiments for bio-pilot run comparisons, technology evaluations, and process improvement initiatives. • Operate and assist in troubleshooting closed-system and automated platforms (e.g., Prodigy, Rotea, Cue, Lovo, G-Rex). • Perform and interpret analytical assays, including flow cytometry, qPCR, ELISA, and other cell-based methods, to support process evaluation and comparability. • Collect, analyze, and summarize experimental data (cell growth, viability, metabolite trends) using statistical tools. • Support preparation of study protocols, technical reports, and SOPs in compliance with GMP standards. • Assist in process troubleshooting and root-cause investigations for manufacturing and automation systems. • Maintain a safe, organized, and compliant laboratory workspace. • Make independent decisions regarding routine laboratory execution, minor troubleshooting, and data analysis within approved study protocols. Requirements • Bachelor's degree in biotechnology, Bioengineering, Molecular Biology, or related discipline. • 2-4 years' experience in cell culture (T-cells, immune cells, or primary cells) in an academic, process development, or GMP environment. • Hands-on experience with aseptic technique and biosafety cabinet work. • Exposure to closed-system or automated manufacturing platforms preferred (e.g., Prodigy, Rotea, Cue, Lovo). • Hands-on experience with analytical assays (flow cytometry, qPCR, ELISA) in a cell therapy, immunology, or bioprocess setting. • Experience in basic analytical methods such as cell counting, viability assays, and metabolite monitoring. • Familiarity with data analysis and preparation of technical documentation. • Proficiency with Microsoft Office (Excel, Word, PowerPoint). • Basic data analysis using Excel, JMP, or similar tools. • Ability to interface with instrument control software. Benefits • Medical, dental, and vision insurance. • 401(k)-retirement plan with company match that vests fully on day one. • Equity and stock options available to employees in eligible roles. • Eight weeks of paid parental leave after just three months of employment. • Paid time off policy that includes 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays. • Flexible spending and health savings accounts. • Life and AD&D insurance. • Short- and long-term disability coverage. • Legal assistance. • Supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. • Commuter benefits. • Family planning and care resources. • Well-being initiatives. • Peer-to-peer recognition programs. Apply tot his job
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